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2001 Sex Determination Lecture 4

"Sexual Evolution: From X to Y" by David C. Page, M.D. Dr. Page interprets the results of an audience-participation experiment comparing testosterone levels in males and females of varying ages. He then explains how the Y chromosome is inherited from father to son in a near clonal fashion. He demonstrates that successive inversions and deletions during mammalian evolution have reduced the Y chromosome to its present form???small and sparsely populated with genes. In some men, a deletion in the Y chromosome can lead to infertility. Dr. Page describes how intracytoplasmic sperm injection can help these men father children.

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HHMI's Holiday Lectures on Science

on Aug 12, 07

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